Small molecules & peptides

TETA-Octreotide acetate

Precursor for radiolabelled TETA-Octreotide

TETA-Octreotide; TETA-OC; CA index name: L-Cysteinamide, N-[[4,8,11-tris(carboxymethyl)-1,4,8,11-tetraazacyclotetradec-1-yl]acetyl]-D-phenylalanyl-L-cysteinyl-L-phenylalanyl- D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide

Sequence: TETA-D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-Thr(ol), cyclic disulfide; TETA = (4,8,11-Triscarboxymethyl-1,4,8,11-tetraaza-cyclotetradec-1-yl)-acetyl; Supplied as acetate salt

Quality

Research Chemical

Characteristics

Molar mass 1433.70

CAS RN [226084-96-4] (net peptide)

Purity ≥ 97 %

  • Colorless to off-white freeze-dried solid

Certificates

CoA: appearance, MS (identity), HPLC (purity)

Literature

Anderson C.J. et al. ⁶⁴Cu-TETA-octreotide as a PET imaging agent for patients with neuroendocrine tumors. J Nucl Med. 2001, 42, 213–21.

Lewis J.S. et al. Radiotherapy and dosimetry of ⁶⁴Cu-TETA-Tyr3-octreotate in a somatostatin receptor-positive, tumor-bearing rat model. Clin Cancer Res. 1999, 5, 3608–16.

Anderson C.J. et al. Radiotherapy, toxicity and dosimetry of copper-64-TETA-octreotide in tumor-bearing rats. J Nucl Med. 1998, 39, 1944–51.

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