Small molecules & peptides

MK-6577 precursor

Precursor for [¹⁸F]MK-6577

2,4-Dichloro-N-[6-chloro-1'-(propane-1-sulfonyl)-2',3',5',6'-tetrahydro-1'H-[2,4']bipyridinyl-4'-ylmethyl]-benzamide; [¹⁸F]MK-6577 precursor

2,4-dichloro-N-{[4-(6-chloropyridin-2-yl)-1-(propylsulfonyl)piperidin-4-yl]methyl}benzamide

Quality

Research Chemical

Characteristics

Molar mass 504.86

CAS RN [not yet assigned]

Purity ≥ 95 %

  • Colorless to off-white solid

Certificates

CoA: appearance, ¹H NMR spectrum

Literature

Hamill T.G. et al. The Synthesis and Preclinical Evaluationin Rhesus Monkey of [¹⁸F]MK-6577 and [¹¹C]CMPyPB Glycine Transporter 1 Positron Emission Tomography Radiotracers. Synapse 2011, 65, 261–270.

Joshi A.D. et al. Characterization of the Novel GlyT1 PET Tracer [¹⁸F]MK-6577 in Humans. Synapse 2015, 69, 33–40.

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