Small molecules & peptides

6-OH-BTA-0 (GMP)

Precursor for [N-Methyl-¹¹C]-6-OH-BTA-1 and precursor for [O-Methyl-¹¹C]-6-MeO-BTA-0

2-(4'-Aminophenyl)-6-hydroxybenzothiazole; Pittsburgh Compound B (PiB)-precursor

CA index name: 6-Benzothiazolol, 2-(4-aminophenyl)-

Quality

GMP Product

Characteristics

Molar mass 242.3

CAS RN [178804-18-7]

Purity ≥ 97 %

  • Yellowish to green solid
  • Tested for bioburden and bacterial endotoxins.

Certificates

CoA: appearance, NMR spectra (identity), HPLC (purity), GC (residual solvents, water content), Content Palladium (ICP-MS), microbiology test

Literature

Mathis C.A. et al. Synthesis and Evaluation of ¹¹C-Labeled 6-Substituted 2-Arylbenzothiazoles as Amyloid Imaging Agents J. Med. Chem. 2003, 46, 2740–2754.

Wilson A.A. et al. A rapid one-step radiosynthesis of the β-amyloid imaging radiotracer N-methyl-[¹¹C]2–4'-methylaminophenyl)-6-hydroxybenzothiazole ([¹¹C]-6-OH-BTA-1) J. Labelled Compd. Radiopharm. 2004, 47, 679–682.

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Product No.: 5101Filling amount: 1 mg
Product No.: 5101Filling amount: 2 mg
Product No.: 5101

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