Small molecules & peptides

N-Desmethyl apalutamide

Precursor for [¹¹C]Apalutamide

JNJ 56142060; Benzamide, 4-​[7-​[6-​cyano-​5-​(trifluoromethyl)​-​3-​pyridinyl]​-​8-​oxo-​6-​thioxo-​5,​7-​diazaspiro[3.4]​oct-​5-​yl]​-​2-​fluoro-

4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluorobenzamide

Quality

Research Chemical

Characteristics

Molar mass 463.41

CAS RN [1332391-11-3]

Purity ≥ 95 %

  • Colorless to off-white solid
  • soluble in dimethyl sulfoxide

Certificates

CoA: appearance, ¹H and ¹⁹F NMR spectra, HPLC

Literature

Boukovala M. et al. An evaluation of apalutamide for the treatment of prostate cancer. Expert Opinion on Pharmacotherapy 2020, 21, 1537–1546.

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