Small molecules & peptides

FAP tartrate

Reference standard for [¹⁸F]FAP

2-Fluoro-A85380 tartrate; 2-Fluoro-3-[2(S)-2-azetidinyl-methoxy]pyridine tartrate

Pyridine, 3-[(2S)-2-azetidinylmethoxy]-2-fluoro-, tartrate

Quality

Research Chemical

Characteristics

Molar mass 332.28

CAS RN [209530-93-8] (free base)

Purity ≥ 95 %

  • Colorless to off-white solid

Certificates

CoA: appearance, ¹H and ¹⁹F NMR spectra

Literature

Ding Y.-S. et al. Synthesis and evaluation of 6-[¹⁸F]fluoro-3-(2(S)- azetidinylmethoxy)pyridine as a PET tracer for nicotinic acetylcholine receptors. Nucl. Med. Biol. 2000, 27, 381–389.

Valette H. et al. Imaging central nicotinic acetylcholine receptors in baboons with [¹⁸F]fluoro-A-85380. J. Nucl. Med. 1999, 40, 1374–1380.

Dollé F. et al. Synthesis and Nicotinic Acetylcholine Receptor in Vivo Binding Properties of 2-Fluoro-3-[2(S)-2-azetidinylmethoxy]pyridine: A New Positron Emission Tomography Ligand for Nicotinic Receptors. J. Med. Chem. 1999, 42, 2251–2259.

Horti A.G. et al. Synthesis of a radiotracer for studying nicotinic acetylcholine receptors: 2-[¹⁸F]fluoro-3-(2(S)-azetidinylmethoxy)-pyridine (2-[¹⁸F]A-85380). J. Labelled Compd. Radiopharm. 1998, 41, 309–318.

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Product No.: 3340Filling amount: 10 mg
Product No.: 3340

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