Small molecules & peptides

DFO*-NCS

Complexation agent for [⁸⁹Zr]-Labelling, immuno-PET

DFO*-pPhe-NCS

5,11,16,22-Tetraazahexacosanediamide, N1-[5-(acetylhydroxyamino)pentyl]-N26,5,16-trihydroxy-N26-[5-[[[(4-isothiocyanatophenyl)amino]thioxomethyl]amino]pentyl]-4,12,15,23-tetraoxo-

Quality

Research Chemical

Characteristics

Molar mass 953.18

CAS RN [1810009-29-0]

Purity ≥ 90 %

  • Colorless to off-white solid

Certificates

CoA: appearance, 1H NMR spectrum (identity), HPLC (purity)

Literature

Patra M. et al. An octadentate bifunctional chelating agent for the development of stable zirconium-89 based molecular imaging probes. Chem. Commun. 2014, 50, 11523–11525.

Vugts D. et al. Comparison of the octadentate bifunctional chelator DFO*-pPhe-NCS and the clinically used hexadentate bifunctional chelator DFO-pPhe-NCS for ⁸⁹Zr-immuno-PET. Eur. J. Nucl. Med. Mol. Imaging. 2017, 44, 286–295.

Heskamp S. et al. ⁸⁹Zr-Immuno-Positron Emission Tomography in Oncology: State-of-the-Art ⁸⁹Zr Radiochemistry. Bioconjugate Chem. 2017, 28, 2211–2223.

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Product No.: 7272

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