Small molecules & peptides
6-O-Desmethyl Donepezil
Precursor for [¹¹C]Donepezil
2-[(1-benzylpiperidin-4-yl)methyl]-6-hydroxy-5-methoxyindan-1-one; 2-((1-benzylpiperidin-4-yl)methyl)-6-hydroxy-5-methoxy-2,3-dihydro-1H-inden-1-one; 1-benzyl-[(6-hydroxy-5-methoxy-1-indanon)-2-yl]methylpiperidine; [¹¹C]Donepezil precursor
2-(1-Benzyl-piperidin-4-ylmethyl)-6-hydroxy-5-methoxy-indan-1-one
Quality
Research Chemical
Characteristics
Molar mass 365.47
CAS RN [120013-56-1]
Purity ≥ 95 %
- Colorless solid
Certificates
CoA: appearance, ¹H NMR spectrum
Literature
De Vos F. et al. Pharmacological evaluation of [¹¹C]donepezil as a tracer for visualization of acetylcholinesterase by PET. Nucl. Med. Biol. 2000, 27, 745–747.
Okamura N. et al. In vivo visualization of donepezil binding in the brain of patients with Alzheimer's disease. Br. J. Clin. Pharmacol. 2008, 65, 472–479.
Gjerløff T. et al. In vivo imaging of human acetylcholinesterase density in peripheral organs using ¹¹C-donepezil: dosimetry, biodistribution, and kinetic analyses. J. Nucl. Med. 2014, 55, 1818–1824.
Gjerløff T. et al. Imaging acetylcholinesterase density in peripheral organs in Parkinson's disease with ¹¹C-donepezil PET. Brain 2015, 138, 653–663.
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| Product | Product No. | Filling amount | Quantity | ||
|---|---|---|---|---|---|
| /products/small-molecules-and-peptides/chemical/203ead93-774b-4db2-8761-d66259ea17bf | Precursor | Product No.: 2162 | Filling amount: 1 mg | ||
| /products/small-molecules-and-peptides/chemical/203ead93-774b-4db2-8761-d66259ea17bf | Precursor | Product No.: 2162 |
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