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Catalogue
Number
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Product
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Order number / Unit
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7510
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S-(-)-IBZM
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7510.0001: 1 mg per vial
7510.0010: 10 mg per vial
Please inquire for customized
filling and bulk quantities.
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Reference standard for S-(-)-[*I]IBZM
Precursor for S-(-)-[123/125I]IBZM
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Molar Mass: 404.24
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C15H21IN2O3
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[84226-06-2]
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Dark yellow oil packaged in dark glass crimp cap vials (7510.0001) or screw cap vials (7510.0010).
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Purity: > 95 %
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Certificates:
CoA; 1H NMR spectrum
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Chemical Name:
CA index name: Benzamide, N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-hydroxy-3-iodo-6-methoxy-
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Synonymes:
Iodobenzamide, (S)-(-)-3-Iodo-2-hydroxy-6-methoxy-N[(1-ethyl-2-pyrrolidinyl)methyl]benzamide
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Literature:
1. Kung H.F. et al. Dopamine D-2 receptor Imaging Radiopharmaceuticals: Synthesis, Radiolabeling and in Vitro binding of R(+)- and S(-)-3-iodo-2-hydroxy-6-methoxy-N-[(1-ethyl-2-pyrrolidinyl)methyl]benzamide. J. Med. Chem. 1988, 31, 1039-1043.
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2. Cordes et al., Initial experience with SPECT examinations using [123I]IBZM as a D2-dopamine receptor antagonist in Parkinson′s disease Eur. J. Radiol. 1991, 12, 182.
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3. Innis R.B. et al. Amphetamine-stimulated dopamine release competes in vivo for [123I]IBZM binding to the D2receptor in nonhuman primates. Synapse 1992, 10, 177.
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4. Ichise M. et al. Iodine-123-IBZM dopamine D2receptor and technetium -99 m-HMPAO brain perfusion SPECT in the evaluation of patients with and subjects at risk for Huntington′s disease J. Nucl. Med. 1993, 34, 1274.
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date of product catalogue issue:
05 April 2012
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