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Catalogue
Number
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Product
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Order number / Unit
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6500
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Dimethyl-8-acetyl-hexahydropyrrolo[2,3]indol-1,2-dicarboxylate
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6500.0010: 10 mg per vial
Please inquire for customized
filling and bulk quantities.
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Precursor for α-[11C]Methyl-L-tryptophan
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Molar Mass: 318.32
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C16H18N2O5
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[79465-83-1]
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Colourless crystals packaged in dark glass screw cap vials.
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Purity: > 95 %
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Certificates:
CoA; 1H NMR spectrum
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Chemical Name:
CA index name: Pyrrolo[2,3-b]indole-1,2(2H)-dicarboxylic acid, 8-acetyl-3,3a,8,8a-tetrahydro-, dimethyl ester, (2α,3a beta,8a beta)-
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Synonymes:
Dimethyl-(2S, 3aR, 8aS)-8-acetyl-1,2,3,3a,8a-hexahydropyrrolo[2,3]indol-1,2-dicarboxylate
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Literature:
1. Shoaf S. et al. The suitability of [11C]-α-methyl-L-tryptophan as a tracer for serotonin synthesis: studies with dual administration of [11C]- and [14C]-labeled tracer. J. Cereb. Blood Flow Metab. 2000, 20, 244-252.
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2. Shoaf S. et al. Brain serotonin synthesis rates in rhesus monkeys determined by [11C]-α-methyl-L-tryptophan and positron emission tomography compared to CSF 5-hydroxyindole-3-acetic acid concentrations. Neuropsychopharmacology 1998, 19, 345-353.
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3. Chakraborty P.K. et al. A high-yield and simplified procedure for the synthesis of α-[11C]methyl-L-tryptophan. Nucl. Med. Biol. 1996, 23, 1005-1008.
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4. Mzengeza S. et al. Asymmetric radiosynthesis of α-[11C]methyl-L-tryptophan for PET studies. Nucl. Med. Biol. 1995, 22, 303-307.
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date of product catalogue issue:
05 April 2012
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