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Catalogue
Number
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Product
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Order number / Unit
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4370
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(+)-McN 5652
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4370.0010: 10 mg per vial
Please inquire for customized
filling and bulk quantities.
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Reference standard for (+)-[11C]McN 5652
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Molar Mass: 681.79
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C19H21NS ⋅ C20H18O8
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[259145-56-7]
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(+)-McN 5652 free base: [103729-16-4]
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Colourless solid packaged in dark glass screw cap vials.
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Purity: > 95 %
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Certificates:
CoA; 1H and 13C NMR spectra
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Chemical Name:
Butanedioic acid, 2,3-bis[(4-methylbenzoyl)oxy]-, (2R,3R)-, compd. with (6S,10bR)-1,2,3,5,6,10b-hexahydro-6-[4-(methylthio)phenyl]pyrrolo[2,1- a]isoquinoline; Pyrrolo[2,1-a]isoquinoline, 1,2,3,5,6,10b-hexahydro-6-[4-(methylthio)phenyl]-, (6S,10bR)-, (2R,3R)-2,3-bis[(4-methylbenzoyl)oxy]butanedioate
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Synonymes:
Pyrrolo[2,1-a]isoquinoline, 1,2,3,5,6,10b-hexahydro-6-[4-(methylthio)phenyl]-, (6S,10bR)-, (2R,3R)-2,3-di-(O-4-methylphenyloxy)butanedioate ; (+)-McN 5652, (-)-di-O-toluyltartrate salt
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Literature:
1. Zessin J. et al. Efficient Synthesis of Enantiomerically Pure Thioester Precursors of [11C]MCN-5652 from Racemic MCN-5652. J. Labelled Compd. Radiopharm. 1999, 42, 1301-12.
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2. Parsey R.V. et al. In Vivo Quantification of Brain Serotonin Transporters in Humans Using [11C]McN 5652. J. Nucl. Med. 2000, 41, 1465-1477.
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3. Buck A. et al. Evaluation of Serotonergic Transporters Using PET and [11C]McN 5652: Assessment of Methods. J. Cereb. Blood Flow Metab. 2000, 20, 253-262.
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4. Suehiro M. et al. An improved method for the synthesis of radiolabeled McN5652 via thioester precursors. Nucl. Med. Biol. 1995, 22, 543-5.
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date of product catalogue issue:
05 April 2012
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