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ABX  advanced biochemical compounds   


Catalogue
Number
Product Order number / Unit

3530 GR 205171 Dihydrochloride 3530.0010: 10 mg per vial
Please inquire for customized filling and bulk quantities.

 
Reference standard for [11C]GR 205171
Molar Mass: 505.36
C21H23F3N6O ⋅ 2 HCl
[168266-51-1]
Yellowish solid packaged in dark glass screw cap vials.
Purity: > 95 %
Certificates:
CoA; 1H, 13C and 19F NMR spectra
Chemical Name:
CA index name: 3-Piperidinamine, N-[[2-methoxy-5-[5-(trifluoro-methyl)-1H-tetrazol-1-yl]phenyl]methyl]-2-phenyl-, dihydrochloride, (2S,3S)-
Synonymes:
3-Piperidinamine, N-[[2-methoxy-5-[5-(trifluoromethyl)-1H-tetrazol-1-yl]phenyl]methyl]-2-phenyl-, dihydrochloride, (2S-cis)-; GR 205171A; Vofopitant dihydrochloride
Literature:
Bergström M. et al. Brain uptake and receptor binding of two [11C]labelled selective high affinity NK1-antagonists, GR203040 and GR205171-PET studies in rhesus monkey. Neuropharmacology 2000, 39, 664-670.
Zamuner S. et al. Estimate the time varying brain receptor occupancy in PET imaging experiments using non-linear fixed and mixed effect modeling approach Nucl. Med. Biol. 2002, 29, 115-123.
Bergström M. et al. A new application of pre-normalized principal component analysis for improvement of image quality and clinical diagnosis in human brain PET studies--clinical brain studies using [11C]-GR205171, [11C]-L-deuterium-deprenyl, [11C]-5-Hydroxy-L-Tryptophan, [11C]-L-DOPA and Pittsburgh Compound-B. Neuroimage 2006, 33, 588-598.
date of product catalogue issue: 08 September 2014

 
 
 

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