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Catalogue
Number
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Product
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Order number / Unit
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3510
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GR 205171
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3510.0010: 10 mg per vial
Please inquire for customized
filling and bulk quantities.
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Reference standard for [11C]GR 205171
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Molar Mass: 432.44
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C21H23F3N6O
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[168266-90-8]
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Yellowish solid packaged in dark glass screw cap vials.
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Purity: > 95 %
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Certificates:
CoA; 1H, 13C and 19F NMR spectra
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Chemical Name:
CA index name: 3-Piperidinamine, N-[[2-methoxy-5-[5-(trifluormethyl)-1H-tetrazol-1-yl]phenyl]methyl]-2-phenyl, (2S,3S)
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Synonymes:
3-Piperidinamine, N-[[2-methoxy-5-[5-(trifluormethyl)-1H-tetrazol-1-yl]phenyl]methyl]-2-phenyl, (2S-cis-); Vofopitant
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Literature:
1. Bergström M. et al. Brain uptake and receptor binding of two [11C]labelled selective high affinity NK1-antagonists, GR203040 and GR205171-PET studies in rhesus monkey. Neuropharmacology 2000, 39, 664-670.
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2. Zamuner S. et al. Estimate the time varying brain receptor occupancy in PET imaging experiments using non-linear fixed and mixed effect modeling approach Nucl. Med. Biol. 2002, 29, 115-123.
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3. Bergström M. et al. A new application of pre-normalized principal component analysis for improvement of image quality and clinical diagnosis in human brain PET studies--clinical brain studies using [11C]-GR205171, [11C]-L-deuterium-deprenyl, [11C]-5-Hydroxy-L-Tryptophan, [11C]-L-DOPA and Pittsburgh Compound-B. Neuroimage 2006, 33, 588-98.
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date of product catalogue issue:
05 April 2012
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