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Catalogue
Number
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Product
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Order number / Unit
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3360
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Nitro-Nifene
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3360.0002: 2 mg per vial
Please inquire for customized
filling and bulk quantities.
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Precursor for [18F]Nifene
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Molar Mass: 321.33
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C15H19N3O5
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[912843-70-0]
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Yellowish oil packaged in dark glass crimp cap vials.
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Purity: > 95 %
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Certificates:
CoA; 1H NMR spectrum
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Chemical Name:
CA index name: 1H-Pyrrole-1-carboxylic acid, 2,5-dihydro-2-[[(2-nitro-3-pyridinyl)oxy]methyl]-, 1,1-dimethylethyl ester, (2S)-
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Synonymes:
2-(2-Nitro-pyridin-3-yl)oxymethyl-2,5-dihydro-pyrrole-1-carboxylic acid tert-butyl ester
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Literature:
1. Mukherjee J. et al. Effect of acetylcholinesterase inhibitors on the binding of nicotinic alpha4beta2 receptor PET radiotracer, (18)F-nifene: A measure of acetylcholine competition. Synapse 2007, 61, 29-36.
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2. Mukherjee J. et al. Nicotinic alpha4beta2 receptor imaging agents. Part II. Synthesis and biological evaluation of 2-[18F]fluoro-3-[2-((S)-3-pyrrolinyl)methoxy]pyridine (18F-nifene) in rodents and imaging by PET in nonhuman primate. Nucl. Med. Biol. 2006, 33, 295-304.
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date of product catalogue issue:
05 April 2012
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