ABX Datasheet Product Number 2950

ABX advanced biochemical compounds


Catalogue Number	Product	Order number / Unit

2950	2′-Deoxy-L-uridine	2950.0010: 10 mg per vial Please inquire for customized filling and bulk quantities.



	Molar Mass: 228.07
	C₉H₁₂N₂O₅
	[31501-19-6]

	Colourless solid packaged in dark glass screw cap vials.


	Purity: > 95 %
	Certificates: CoA; ¹H and ¹³C NMR spectra
	Chemical Name: CA index name: 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-β-L-erythro-pentofuranosyl)
	Synonymes: 1-(2′-Deoxy-β-L-erythro-pentofuranosyl)uracil; 2′-Deoxy-L-uridine; β-L-2′-deoxyuridine
	Literature: 1. Spadari S. et al. L-Thymidine is phosphorylated by herpes simplex virus type 1 thymidine kinase and inhibits viral growth. J. Med. Chem. 1992, 35, 4214-4220.
	2. Maga G. et al. Lack of stereospecificity of suid pseudorabies virus thymidine kinase. Biochem. J. 1993, 294, 381-385.
	3. Kouni M.H. et al. Effects of modifications in the pentose moiety and conformational changes on the binding of nucleoside ligands to uridine phosphorylase from Toxoplasma gondii. Biochem. Pharmacol. 1996, 51, 1687-1700.
	4. Verri A. et al. Lack of enantiospecificity of human 2′-deoxycytidine kinase: relevance for the activation of beta.-L-deoxycytidine analogs as antineoplastic and antiviral agents. Mol. Pharmacol. 1997, 51, 132-138.

	date of product catalogue issue: 05 April 2012