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ABX  advanced biochemical compounds   


Catalogue
Number
Product Order number / Unit

1611 (R,S)-PK11195 1611.0010: 10 mg per vial
Please inquire for customized filling and bulk quantities.

 
Reference standard for (R,S)-[N-Methyl-11C]PK11195
Molar Mass: 352.86
C21H21ClN2O
[85532-75-8]
Yellowish oil packaged in dark glass screw cap vials.
Purity: > 95 %
Certificates:
CoA; 1H NMR spectrum
Chemical Name:
CA index name: 3-Isoquinolinecarboxamide, 1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)-, (RS)
Synonymes:
1-(2-Chlorophenyl)-N-methyl-N-(1-methylpropyl)-isoquinoline-3-carboxamide-(RS); PK11195; RP 52028
Literature:
1. Camsonne R. et al. Synthesis of N-[11C]methyl, N-(methyl-1-propyl), (chloro-2-phenyl)-1-isoquinoline carboxamide-3 (PK11195): a new ligand for peripheral benzodiazepine receptors. J. Labelled Compd. Radiopharm. 1984, 21, 985-991.
2. Hashimoto K. et al. Synthesis and evaluation of 11C-PK11195 for in vivo study of peripheral-type benzodiazepine receptors using positron emission tomography. Ann. Nucl. Med. 1989, 3, 63-71.
3. Shah F. et al. Synthesis of the Enantiomers of [N-methyl-11C]PK 11195 and Comparison of their Behaviours as Radioligands for PK Binding Sites in Rats. Nucl. Med. Biol. 1994, 21, 573-581.
4. Cremer J.E. et al. The Distribution of Radioactivity in Brains of Rats Given [N-methyl-11C]PK11195 In Vivo After Induction of a Cortical Ischaemic Lesion. Int. J. Rad. Appl. Instrum. B, 1992, 19, 159-166.
date of product catalogue issue: 04 October 2013

 
 
 

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