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Catalogue
Number
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Product
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Order number / Unit
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1611
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(R,S)-PK11195
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1611.0010: 10 mg per vial
Please inquire for customized
filling and bulk quantities.
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Reference standard for (R,S)-[N-Methyl-11C]PK11195
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Molar Mass: 352.86
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C21H21ClN2O
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[85532-75-8]
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Yellowish oil packaged in dark glass screw cap vials.
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Purity: > 95 %
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Certificates:
CoA; 1H NMR spectrum
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Chemical Name:
CA index name: 3-Isoquinolinecarboxamide, 1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)-, (RS)
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Synonymes:
1-(2-Chlorophenyl)-N-methyl-N-(1-methylpropyl)-isoquinoline-3-carboxamide-(RS); PK11195; RP 52028
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Literature:
1. Camsonne R. et al. Synthesis of N-[11C]methyl, N-(methyl-1-propyl), (chloro-2-phenyl)-1-isoquinoline carboxamide-3 (PK11195): a new ligand for peripheral benzodiazepine receptors. J. Labelled Compd. Radiopharm. 1984, 21, 985-991.
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2. Hashimoto K. et al. Synthesis and evaluation of 11C-PK11195 for in vivo study of peripheral-type benzodiazepine receptors using positron emission tomography. Ann. Nucl. Med. 1989, 3, 63-71.
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3. Shah F. et al. Synthesis of the Enantiomers of [N-methyl-11C]PK 11195 and Comparison of their Behaviours as Radioligands for PK Binding Sites in Rats. Nucl. Med. Biol. 1994, 21, 573-581.
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4. Cremer J.E. et al. The Distribution of Radioactivity in Brains of Rats Given [N-methyl-11C]PK11195 In Vivo After Induction of a Cortical Ischaemic Lesion. Int. J. Rad. Appl. Instrum. B, 1992, 19, 159-166.
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date of product catalogue issue:
21 Decmber 2012
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