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ABX  advanced biochemical compounds   

Catalogue
Number 		Product Order number / Unit
1200 Dimethoxybenzyl-FLT-precursor 1200.0010: 10 mg per vial
1200.0025: 25 mg per vial
Please inquire for customized filling and bulk quantities.
Precursor for [18F]FLT
(3′-Deoxy-3′-[18F]fluorothymidine)
Molar Mass: 879.93
C46H45N3O13S
[290371-75-4]
Yellowish to orange foam packaged in dark glass crimp cap vials.
Purity: > 95 %
Certificates:
CoA; 1H NMR spectrum
Chemical Name:
CA index name: 2,4-(1H,3H)-Pyrimidinedione, 1-[5-O-[bis(4-methoxy-phenyl)phenylmethyl]-2-deoxy-3-O-[(4-nitrophenyl)sulfonyl]-beta-D-threo-pentofuranosyl]-3-[(2,4-dimethoxyphenyl)methyl]-5-methyl-
Synonymes:
3-N-(2,4-Dimethoxybenzyl)-1-[5-O-(4,4′-dimethoxytrityl)-3-O-nitrophenylsulfonyl-2-deoxy-beta-D-lyxofuranosyl]thymidine; N-(2,4-Dimethoxybenzyl)-5′-O-dimethoxytrityl-3′-O-nosyl-thymidine; 2,4-(1H,3H)-Pyrimidinedione, 1-[5-O-[bis(4-methoxy-phenyl)phenylmethyl]-2-deoxy-3-O-[(4-nitrophenyl)sulfonyl]-beta-D-threo-pentofuranosyl]-3-[(2,4-dimethoxyphenyl)methyl]-5-methyl-; Dimethylbenzyl-FLT-precursor
Literature:
1. Shields A.F. et al. Imaging proliferation in vivo with [18F]FLT and positron emission tomography. Nature Medicine 1998, 4, 1334-1336.
2. Grierson J.R. et al. Developments in the radiosynthesis of [18F]FLT. J. Nucl. Med. 1998, 39, Proceedings of the 45th Annual Meeting, Toronto, Ontario, Canada; 22 P. No. 76.
3. Grierson J.R. et al. An improved radiosynthesis of [18F]FLT. J. Labelled Compd. Radiopharm. 1999, 42, Suppl. 1, S525.
4. Grierson J.R. et al. Radiosynthesis of 3′-deoxy-3′-[18F]fluoro-thymidine: [18F]FLT for imaging of cellular proliferation in vivo. Nucl. Med. Biol. 2000, 27, 143-156.
date of product catalogue issue: 31 August 2010

 
 
 

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