ABX Datasheet Product Number 1190

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ABX advanced biochemical compounds


Catalogue Number	Product	Order number / Unit

1190	DMTr-Nosyl-lyxothymidine	1190.0010: 10 mg per vial 1190.0020: 20 mg per vial 1190.0025: 25 mg per vial 1190.0030: 30 mg per vial 1190.0040: 40 mg per vial Please inquire for customized filling and bulk quantities.
	Precursor for [¹⁸F]FLT (3′-Deoxy-3′-[¹⁸F]fluorothymidine)


	Molar Mass: 729.75
	C₃₇H₃₅N₃O₁₁S
	[444717-20-8]

	Yellowish amorphous solid packaged in dark glass crimp cap vials.


	Purity: > 90 %
	Certificates: CoA; ¹H NMR spectrum
	Chemical Name: CA index name: 2,4(1H,3H)-Pyrimidinedione, 1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-3-O-[(4-nitrophenyl)sulfonyl]- β-D-threo-pentofuranosyl]-5-methyl-
	Synonymes: 1-[5-O-(4,4′-Dimethoxytrityl)-3-O-nitrophenylsulfonyl-2-deoxy-β-D-lyxofuranosyl]thymine; 5′-O-Dimethoxytrityl-3′-O-nosyl-thymidine; 1-[5-O-(4,4′-Dimethoxytrityl)-3-O-nitrophenylsulfonyl-2-deoxy-β-D-threo-pentofuranosyl]-thymine; 2,4(1H,3H)-Pyrimidinedione, 1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-3-O-[(4-nitrophenyl)sulfonyl]-β-D-threo-pentofuranosyl]-5-methyl-; DMTr-Nosyl-lyxothymidine; Non-Boc-FLT
	Literature: 1. Oh S.J. et al. High radiochemical yield synthesis of 3′-deoxy-3′-[¹⁸F]Fluorothymidine using (5′-O-dimethoxytrityl-2′-deoxy-3′-O-nosyl-β-D-threo-pentofuranosyl)thymine and its 3-N-BOC-protected analogue as a labeling precursor. Nucl. Med. Biol. 2003, 30, 151-157.
	2. Eisenhut M. et al. A new precursor for the radiosynthesis of [¹⁸F]FLT. Nucl. Med. Biol. 2002, 29, 263-273.



	date of product catalogue issue: 22 December 2011

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