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ABX  advanced biochemical compounds   

Catalogue
Number 		Product Order number / Unit
1190 DMTr-Nosyl-lyxothymidine 1190.0010: 10 mg per vial
1190.0020: 20 mg per vial
1190.0025: 25 mg per vial
1190.0030: 30 mg per vial
1190.0040: 40 mg per vial
Please inquire for customized filling and bulk quantities.
Precursor for [18F]FLT
(3′-Deoxy-3′-[18F]fluorothymidine)
Molar Mass: 729.75
C37H35N3O11S
[444717-20-8]
Yellowish amorphous solid packaged in dark glass crimp cap vials.
Purity: > 90 %
Certificates:
CoA; 1H NMR spectrum
Chemical Name:
CA index name: 2,4(1H,3H)-Pyrimidinedione, 1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-3-O-[(4-nitrophenyl)sulfonyl]- beta -D-threo-pentofuranosyl]-5-methyl-
Synonymes:
1-[5-O-(4,4′-Dimethoxytrityl)-3-O-nitrophenylsulfonyl-2-deoxy-beta-D-lyxofuranosyl]thymine; 5′-O-Dimethoxytrityl-3′-O-nosyl-thymidine; 1-[5-O-(4,4′-Dimethoxytrityl)-3-O-nitrophenylsulfonyl-2-deoxy-beta-D-threo-pentofuranosyl]-thymine; 2,4(1H,3H)-Pyrimidinedione, 1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-3-O-[(4-nitrophenyl)sulfonyl]-beta-D-threo-pentofuranosyl]-5-methyl-; DMTr-Nosyl-lyxothymidine; Non-Boc-FLT
Literature:
1. Oh S.J. et al. High radiochemical yield synthesis of 3′-deoxy-3′-[18F]Fluorothymidine using (5′-O-dimethoxytrityl-2′-deoxy-3′-O-nosyl-beta-D-threo-pentofuranosyl)thymine and its 3-N-BOC-protected analogue as a labeling precursor. Nucl. Med. Biol. 2003, 30, 151-157.
2. Eisenhut M. et al. A new precursor for the radiosynthesis of [18F]FLT. Nucl. Med. Biol. 2002, 29, 263-273.
date of product catalogue issue: 31 August 2010

 
 
 

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