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Catalogue
Number
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Product
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Order number / Unit
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102
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Mannose Triflate, ultra pure
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102.0020: 20 mg per vial
102.0030: 30 mg per vial
Please inquire for customized
filling and bulk quantities.
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Precursor for [18F]FDG
(2-[18F]Fluoro-2-deoxy-D-glucose)
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packing for FDG MicroLab (GE)
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Molar Mass: 480.37
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C15H19F3O12S
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[92051-23-5]
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Colourless or nearly colourless crystals packaged in 2 ml dark glass vials ( for GE Microlab) with teflon-faced rubber stoppers, tear-off crimp caps, argon flushed.
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Melting range 119 - 122 degC
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Soluble in acetonitrile, DMSO, methanol, acetone; insoluble in aqueous media.
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Purity: > 99 %
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Certificates:
CoA; melting point, 1H and 19F NMR spectra, IR spectrum, HPLC
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Chemical Name:
CA index name: beta-D-mannopyranose, 1,3,4,6-tetraacetate 2-(trifluoromethane-sulfonate)
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Synonymes:
TATM; mannose triflate; 1,3,4,6-tetra-O-acetyl-2-O-trifluoro-methanesulfonyl-beta-D-mannopyranose
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Literature:
1. Hamacher K. et al. Efficient stereospecific synthesis of no-carrier-added 2-[18F]fluoro-2-deoxy-D-glucose using amino-polyether supported nucleophilic substitution. J. Nucl. Med. 1986, 27, 235-238.
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2. Padgett H. et al. Computer-controlled radiochemical synthesis: a chemistry process control unit for the automated production of radiochemicals. Appl. Radiat. Isot. 1989, 40, 433-445.
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3. Pavliak V. et al. A short synthesis of 1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-beta-D-glucopyranose and the corresponding alpha-glucosyl chloride from D-mannose. Carbohydr. Res. 1991, 210, 333-337.
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4. Chirakal R. Traces of fluorine containing impurities in the mannose triflate and their adverse effect on the radiochemical yield of 2-18FDG. XIIth ISRC; Uppsala, Sweden 1997, 214-216.
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date of product catalogue issue:
21 Decmber 2012
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